Key result
Simultaneous CABG and mitral valve surgery carries ~13% early mortality, driven by age and NYHA class.
Why the study?
The combination of coronary artery bypass grafting and mitral valve surgeries is associated with high in-hospital mortality and morbidity, necessitating analysis of factors influencing early mortality.
Cohort (n=68)
Simultaneous CABG and mitral valve surgery for ischemic mitral insufficiency carries a 13.2% early mortality rate, strongly predicted by advanced age, severe heart failure symptoms, and poor left ventricular function.
High early mortality after combined CABG and mitral surgery cautions against unselected use in elderly or NYHA ≥3 patients; leaves open optimal strategies pending randomized data.
BACKGROUND: The combination of coronary artery bypass grafting and mitral valve surgeries is closely associated with high in-hospital mortality and morbidity. In this study, we sought to analyze the factors that influence early mortality in 68 patients undergoing coronary artery bypass grafting + mitral valve surgery due to ischemic mitral insufficiency. METHODS: Of 1183 patients undergoing coronary bypass surgery between April 2002 and June 2006, 68 patients (42 male and 26 female) 42 to 78 years of age (mean +/- SD, 59.3 +/- 9.1) underwent mitral valve surgery accompanying coronary bypass surgery (survival, n = 59; mortality, n = 9). The cases were analyzed regarding the demographic, preoperative, and perioperative risk factors that influence mortality. RESULTS: The early mortality rate was found to be 13.2% (9/68) in patients with ischemic mitral regurgitation undergoing simultaneous coronary bypass and mitral valve surgeries. New York Heart Association class > or =3, left ventricle end-systolic volume, left ventricle end-systolic diameter, cardiopulmonary perfusion time, preoperative unstable angina pectoris, intra-aortic balloon application, and age >65 years were determined to be statistically significant risk factors that influence early in-hospital mortality.Conclusion. Surgery, despite having a high mortality risk in patients with ischemic mitral insufficiency, is considered to be a treatment measure that generally improves the quality of life and prolongs life.
No takes yet. Share an insight, caveat, or question.
Burma et al. (2007) conducted a cohort in Chronic Ischemic Mitral Insufficiency (n=68). Demographic, preoperative, and perioperative risk factors was evaluated on Early in-hospital mortality. Simultaneous coronary bypass and mitral valve surgery for ischemic mitral insufficiency had an early mortality rate of 13.2%, with NYHA class ≥3 and age >65 years as significant risk factors.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: