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July 9, 2025Journal of Clinical MedicineOpen Access

Ischemic Mitral Valve Regurgitation in Patients Undergoing Coronary Artery Bypass Grafting—Early and Late-Term Outcomes of Surgical Treatment

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Why the study?

Data regarding the efficacy of surgical interventions and the determinants of postoperative outcomes for ischemic mitral regurgitation remain inconclusive.

Does concomitant mitral valve surgery and CABG improve early and long-term mortality in patients with ischemic mitral regurgitation?

Population

421 patients with ischemic mitral regurgitation undergoing concomitant mitral valve surgery and CABG

Comparison

Mitral valve repair vs mitral valve replacement

Design

Retrospective cohort study

Authors

PWPaweł WalerowiczPomeranian Medical UniversityMBMirosław BrykczyńskiFoundation of Cardiac Surgery DevelopmentASAleksandra SzylińskaPomeranian Medical University

Discussion

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Implication

Mortality aligns with EuroSCORE II predictions for mitral surgery plus CABG in ischemic MR; leaves optimal repair strategy open.

Structured PICO

Does concomitant mitral valve surgery and CABG improve early and long-term mortality in patients with ischemic mitral regurgitation?

P
Population
421 patients diagnosed with ischemic mitral regurgitation undergoing concomitant mitral valve surgery and CABG. Mean age 65.7, 65.1% male. Excluded emergent and urgent procedures as well as non-ischemic etiologies of mitral valve dysfunction.
I
Intervention
Concomitant mitral valve surgery (repair [n=344] or replacement [n=77]) and coronary artery bypass grafting (CABG)
O
Outcome
Early and long-term outcomes (mortality and morbidity)hard clinical

Concomitant mitral valve surgery during CABG for ischemic mitral regurgitation demonstrates acceptable mortality rates that align with EuroSCORE II predictions, though reduced LVEF and advanced symptoms predict worse long-term outcomes.

Cite This Study

Walerowicz et al. (2025) studied this question.

synapsesocial.com/papers/6a105850d13714ec96ffa699https://doi.org/10.3390/jcm14144855

Topics

Mitral valve intervention
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcome of Patients Sustaining Acute Ischemic Mitral Regurgitation during Myocardial Infarction1992 · 262 citations
  2. 2Timing of mitral valve surgery2002 · 115 citations
  3. 3Combined Papillary Muscle and Left Ventricular Wall Dysfunction as a Cause of Mitral Regurgitation1971 · 145 citations
  4. 4Echocardiographic Assessment of Ischaemic Mitral Regurgitation, Mechanism, Severity, Impact on Treatment Strategy and Long Term Outcome2016 · 17 citations
  5. 5Restrictive Annuloplasty and Coronary Revascularization in Ischemic Mitral Regurgitation Results in Reverse Left Ventricular Remodeling2004 · 353 citations