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November 16, 2023International Surgery JournalOpen Access

Ten-year outcomes of surgical treatment of ischemic mitral regurgitation-a retrospective study

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Key result

CABG with or without mitral surgery links to 10-year functional improvement and reduced MR severity.

  • n=68

Why the study?

The study aimed to investigate the long-term outcomes of patients with ischemic mitral regurgitation after undergoing CABG with or without mitral valve repair or replacement.

Does CABG with or without mitral valve repair or replacement improve long-term outcomes in patients with ischemic mitral regurgitation?

Population

68 patients with ischemic MR

Comparison

CABG only vs CABG+MVR vs CABG+MVr

Design

Retrospective observational study

Follow-up

10 years

Authors

AVAnshuman VajpeyiVPVarghese T. Panicker

Discussion

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Overview

May support CABG ± mitral intervention in ischemic MR; extends observational data but leaves randomized confirmation open.

Study Design

Type

Observational (n=68)

Multicenter

No

Structured PICO

Does CABG with or without mitral valve repair or replacement improve long-term outcomes in patients with ischemic mitral regurgitation?

P
Population
68 patients with coronary artery disease and ischemic mitral regurgitation who underwent CABG with or without mitral valve repair or replacement, followed for up to 10 years.
E
Exposure
Coronary artery bypass graft (CABG) with or without mitral valve repair (MVr) or mitral valve replacement (MVR)
C
Comparator
Comparison between three surgical groups: CABG only, CABG+MVR, and CABG+MVr
O
Outcome
Long-term outcomes including New York Heart Association (NYHA) functional class, MR status, redo surgery rates, and mortality at 3 months, 1 year, and 10 yearscomposite

Surgical interventions including CABG with or without mitral valve repair or replacement effectively improve functional outcomes and reduce MR severity in patients with ischemic mitral regurgitation over a 10-year period.

Limitations

  • Information bias due to retrospective design
  • Small sample size limiting generalizability
  • Single-center study
  • Relatively small sample size limiting generalizability

Cite This Study

Vajpeyi et al. (2023) conducted an observational in Ischemic mitral regurgitation (n=68). Coronary artery bypass graft (CABG) with or without mitral valve repair or replacement vs. Between-group comparison (CABG only vs CABG+MVR vs CABG+MVr) was evaluated on Improvement in NYHA functional class and MR status. Coronary artery bypass graft surgery with or without mitral valve repair or replacement effectively improved functional outcomes and reduced MR severity over 10 years in patients with ischemic MR.

synapsesocial.com/papers/6a209bb839c1aa3df691ccbbhttps://doi.org/10.18203/2349-2902.isj20233544
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mitral Valve Repair Versus Revascularization Alone in the Treatment of Ischemic Mitral Regurgitation2006 · 169 citations
  2. 2Surgical Treatment of Moderate Ischemic Mitral Regurgitation2014 · 420 citations
  3. 3Predictors of sudden cardiac death in atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study2017 · 11 citations
  4. 4Global Burden of Cardiovascular Diseases and Risks, 1990-20222023 · 1,656 citations