Key result
Conjoint mitral valve replacement and CABG significantly improved mean left ventricular ejection fraction from 40.75% at baseline to 52.86% at one year (p<0.001).
Why the study?
Guidelines do not clearly favor mitral valve repair over replacement for moderate-to-severe IMR due to contradictory and inconclusive evidence.
Does conjoint CABG and MVR improve LV function and clinical outcomes in patients with moderate-to-severe ischemic mitral regurgitation?
Comparison
CABG and MVR
Design
Retrospective study
Follow-up
One year
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May support conjoint CABG-MVR in ischemic MR; leaves open randomized confirmation of LVEF gains.
Observational (n=23)
Does conjoint CABG and MVR improve LV function and clinical outcomes in patients with moderate-to-severe ischemic mitral regurgitation?
Absolute Event Rate: 52.86% vs 40.75%
p-value: p=<0.001
Conjoint MVR and CABG for moderate-to-severe ischemic mitral regurgitation is associated with high one-year survival and significant improvement in LV systolic function and functional status.
A 2024 study conducted an observational in Ischemic heart disease with moderate-to-severe ischemic mitral regurgitation (n=23). Mitral valve replacement (MVR) and coronary artery bypass grafting (CABG) was evaluated on Left ventricular ejection fraction (LVEF) at one year (p=<0.001). Conjoint mitral valve replacement and CABG significantly improved mean left ventricular ejection fraction from 40.75% at baseline to 52.86% at one year (p<0.001).
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