Key result
Mitral valve repair for severe ischemic mitral regurgitation had similar 5-year survival compared to replacement (64% vs 64%, P=0.41) but lower operative mortality (8% vs 16%, P=0.04).
Why the study?
This study evaluated outcomes of mitral valve surgery for severe ischemic mitral regurgitation.
Does mitral valve repair compared to mitral valve replacement improve survival and reduce complications in patients undergoing CABG for severe ischemic mitral regurgitation?
Population
358 patients undergoing CABG with concomitant MVr or MVR for severe IMR
Comparison
MVr vs MVR concomitant with CABG
Design
Single-center retrospective cohort study
Follow-up
5 years
Authors
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Repair may lower operative mortality in ischemic MR; leaves open need for randomized confirmation of survival equivalence.
Cohort (n=358)
No
Does mitral valve repair compared to mitral valve replacement improve survival and reduce complications in patients undergoing CABG for severe ischemic mitral regurgitation?
Absolute Event Rate: 64% vs 64%
p-value: p=.41
In patients with severe ischemic mitral regurgitation undergoing CABG, mitral valve repair offers similar 5-year survival to replacement but with lower operative mortality and readmission rates.
Dufendach et al. (2019) conducted a cohort in Severe ischemic mitral regurgitation (n=358). Mitral valve repair (MVr) vs. Mitral valve replacement (MVR) was evaluated on 5-year survival (p=.41). Mitral valve repair for severe ischemic mitral regurgitation had similar 5-year survival compared to replacement (64% vs 64%, P=0.41) but lower operative mortality (8% vs 16%, P=0.04).
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