Why the study?
Does mitral valve repair reduce mortality compared to mitral valve replacement in patients with ischemic mitral regurgitation?
Population
4,066 patients with ischemic mitral regurgitation pooled from 22 observational studies and 1 RCT.
Comparison
Mitral valve repair (MVr) vs Mitral valve replacement (MVR)
Design
Meta-analysis
Authors
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Supports preferring MVr over MVR to reduce mortality in ischemic MR; extends meta-analytic evidence from observational data.
Does mitral valve repair reduce mortality compared to mitral valve replacement in patients with ischemic mitral regurgitation?
Mitral valve repair is associated with reduced peri-operative and late mortality compared to replacement in ischemic mitral regurgitation, despite higher rates of recurrent MR.
Virk et al. (2015) studied this question.
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