Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 20, 2010European Journal of Cardio-Thoracic SurgeryOpen Access

Meta-analysis of short-term and long-term survival following repair versus replacement for ischemic mitral regurgitation

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does mitral valve repair improve short-term and long-term survival compared to mitral valve replacement in patients with ischemic mitral regurgitation?

Population

Patients with ischemic mitral regurgitation from 9 retrospective studies. Most patients had concomitant…

Comparison

Mitral valve repair vs Mitral valve replacement

Design

Meta-analysis

Authors

CVChristina M. VassilevaTBTheresa M. BoleySMStephen Markwell

Discussion

Loading...

Member takes

Overview

Supports mitral valve repair over replacement for ischemic mitral regurgitation; leaves open confirmation via randomized trials before practice change.

Structured PICO

Does mitral valve repair improve short-term and long-term survival compared to mitral valve replacement in patients with ischemic mitral regurgitation?

P
Population
Patients with ischemic mitral regurgitation (IMR) from 9 retrospective studies. Most patients had concomitant coronary artery bypass graft. Excluded patients with degenerative etiology.
I
Intervention
Mitral valve repair
C
Comparator
Mitral valve replacement (with preservation of at least the posterior and often the entire subvalvular apparatus)
O
Outcome
Short-term mortality and long-term mortalityhard clinical

In patients with ischemic mitral regurgitation, mitral valve repair is associated with better short-term and long-term survival compared to mitral valve replacement based on retrospective observational data.

Limitations

  • Meta-analysis of retrospective studies
  • Heterogeneity of patient characteristics
  • Selection bias influencing physician's decision to perform repair or replacement

Cite This Study

Vassileva et al. (2010) studied this question.

synapsesocial.com/papers/6a7579f4f2cd31a1fadc1507https://doi.org/10.1016/j.ejcts.2010.06.034
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Outcomes following Mitral Valve Repair versus Replacement for Chronic Ischemic Mitral Regurgitation: A Meta-Analysis2016 · 20 citations
  2. 2The effect of pathophysiology on the surgical treatment of ischemic mitral regurgitation: operative and late risks of repair versus replacement1995 · 206 citations
  3. 3A meta-analysis of mitral valve repair versus replacement for ischemic mitral regurgitation.2015 · 29 citations
  4. 4Repair or replacement for severe ischemic mitral regurgitation2018 · 20 citations
  5. 5Severe mitral regurgitation requiring surgery: comparison of repair versus replacement2024