Why the study?
Mitral regurgitation is a common valvular heart disease, but the comparative outcomes and complications of mitral valve replacement versus surgical mitral valve repair for non-ischemic mitral regurgitation required systematic evaluation.
Does surgical mitral valve repair improve survival and reduce complications compared to mitral valve replacement in patients with non-ischemic mitral regurgitation?
Population
21,898 patients with non-ischemic mitral regurgitation across 20 studies
Comparison
Mitral valve replacement vs surgical mitral valve repair
Design
Systematic review and meta-analysis
Authors
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MV repair linked to better survival and fewer complications than replacement in NIMR; supports repair preference but leaves open need for RCTs.
Does surgical mitral valve repair improve survival and reduce complications compared to mitral valve replacement in patients with non-ischemic mitral regurgitation?
In patients with non-ischemic mitral regurgitation, surgical mitral valve repair is associated with lower early and late mortality and fewer complications compared to valve replacement.
Fan et al. (2021) studied this question.
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