What question did this study set out to answer?

To describe the clinical presentation, diagnosis, and multimodal treatment approach for an exceptionally rare case of small cell neuroendocrine carcinoma of the bladder presenting with regional lymph node metastasis.

September 18, 2026CureusOpen Access

Small Cell Neuroendocrine Carcinoma of the Bladder With Lymph Node Metastases: A Case Report

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Authors

SOSouad El OurdiCentre Hospitalier Universitaire Mohammed VI OZOthmane ZouitenCentre Hospitalier Universitaire Mohammed VI LALeila AfaniCadi Ayyad University

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Implication

Case report demonstrates multimodal management of small cell neuroendocrine carcinoma in a 62-year-old female, highlighting early systemic chemotherapy for rare bladder malignancies.

Key Points

To describe the clinical presentation, diagnosis, and multimodal treatment approach for an exceptionally rare case of small cell neuroendocrine carcinoma of the bladder presenting with regional lymph node metastasis.
Assessed a 62-year-old female presenting with inguinal lymphadenopathy indicative of metastatic disease.
Conducted a transurethral resection of the bladder tumor (TURBT) with double-J ureteral stent placement to establish histological confirmation.
Initiated first-line systemic chemotherapy using an etoposide and carboplatin regimen.
Histopathological analysis confirmed small cell neuroendocrine carcinoma of the bladder, an entity comprising less than one percent of bladder neoplasms.
Staging revealed early locoregional metastatic involvement demonstrated by inguinal lymphadenopathy.

Cite This Study

Ourdi et al. (2026) studied this question.

synapsesocial.com/papers/6aad0afede0393d728b893da https://doi.org/10.7759/cureus.116353

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Implication

Case report demonstrates multimodal management of small cell neuroendocrine carcinoma in a 62-year-old female, highlighting early systemic chemotherapy for rare bladder malignancies.

Small Cell Neuroendocrine Carcinoma of the Bladder With Lymph Node Metastases: A Case Report

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Implication

Key Points

Cite This Study

Small Cell Neuroendocrine Carcinoma of the Bladder With Lymph Node Metastases: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

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