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September 18, 2026Malaria JournalOpen Access

Umbrella review and meta-analysis on malaria infection and associated factors among pregnant women in Africa, 2026

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Authors

HAHabtamu AyeleDebre Markos UniversityGMGeremew MekonenDebre Markos UniversityTATesfahun AyenewDebre Markos University

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Implication

Umbrella review reveals high malaria prevalence and environmental risks in pregnant African women, highlighting insecticide-treated bed nets for targeted prevention.

Key Points

  • To synthesize evidence from existing systematic reviews and meta-analyses to estimate the pooled prevalence of malaria infection and identify associated risk factors among pregnant women in Africa.
  • Conducted an umbrella review following PRIOR and Joanna Briggs Institute guidelines across six international databases from February 2016 to February 2026.
  • Synthesized data from 10 high-quality systematic reviews assessed by AMSTAR-2, encompassing 139,256 participants, using a random-effects model.
  • The overall pooled prevalence of malaria infection among pregnant women was 20.74% (95% CI: 14.07–27.41; I² = 99.85%), with regional estimates ranging between 6.49% and 34.3%.
  • Significant risk factors included non-use of insecticide-treated nets (AOR: 4.31; 95% CI: 1.37–7.24) and proximity to stagnant water bodies (AOR: 4.21; 95% CI: 2.13–6.30).

Cite This Study

Ayele et al. (2026) studied this question.

synapsesocial.com/papers/6aad0b86de0393d728b89dcehttps://doi.org/10.1186/s12936-026-06157-8
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