Key result
PCPS and mechanical ventilation rescue a patient from cardiac arrest following ergonovine-induced intractable coronary spasm.
Why the study?
Ergonovine-induced coronary artery spasm can cause serious cardiovascular complications that are sometimes medically intractable, requiring advanced supportive care.
Case Report (n=1)
Percutaneous cardiopulmonary support (PCPS) can be a life-saving intervention for patients experiencing medically intractable coronary spasm and cardiac arrest during ergonovine provocation testing.
May support PCPS rescue in ergonovine-induced arrest; hypothesis-generating and should not yet change practice.
The ergonovine provocation test is often used in diagnosing variant angina. Most patients with an ergonovine-induced coronary artery spasm respond promptly to intracoronary nitroglycerin administration within 3 to 5 minutes. However, in a few patients ergonovine results in serious cardiovascular complications due to intractable coronary artery spasm. We report a case of a severe and medically intractable coronary spasm induced by ergonovine, followed by cardiac arrest. Aided by percutaneous cardiopulmonary support (PCPS) and mechanical ventilation, the patient could survive after four days of hospitalization despite a recurrent vasospasm. Recovery was largely attributed to full supportive care and the use of PCPS.
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Kang et al. (2012) conducted a case report in Medically intractable coronary spasm induced by ergonovine, followed by cardiac arrest (n=1). Percutaneous cardiopulmonary support (PCPS) and mechanical ventilation was evaluated on Survival and recovery. Percutaneous cardiopulmonary support (PCPS) and mechanical ventilation enabled the survival and recovery of a patient who experienced cardiac arrest from ergonovine-induced intractable coronary spasm.
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