Key result
Internet-based multidomain intervention improves cardiovascular risk profiles in older adults.
Why the study?
Many dementia and cardiovascular disease cases in older adults are attributable to modifiable vascular and lifestyle-related risk factors, providing opportunities for prevention.
Can an internet-based multidomain intervention be designed based on European guidelines to improve cardiovascular risk in older adults?
RCT (n=2,500)
Yes
Can an internet-based multidomain intervention be designed based on European guidelines to improve cardiovascular risk in older adults?
An internet-based multidomain intervention for cardiovascular and cognitive prevention in older adults can be successfully designed and harmonized across different European national guidelines.
Supports scalable digital CV prevention in older adults; extends feasibility evidence to harmonized multinational guideline-based trials.
BACKGROUND: Many dementia and cardiovascular disease (CVD) cases in older adults are attributable to modifiable vascular and lifestyle-related risk factors, providing opportunities for prevention. In the Healthy Aging Through Internet Counselling in the Elderly (HATICE) randomized controlled trial, an internet-based multidomain intervention is being tested to improve the cardiovascular risk (CVR) profile of older adults. OBJECTIVE: To design a multidomain intervention to improve CVR, based on the guidelines for CVR management, and administered through a coach-supported, interactive, platform to over 2500 community-dwellers aged 65+ in three European countries. METHODS: A comparative analysis of national and European guidelines for primary and secondary CVD prevention was performed. Results were used to define the content of the intervention. RESULTS: The intervention design focused on promoting awareness and self-management of hypertension, dyslipidemia, diabetes mellitus, and overweight, and supporting smoking cessation, physical activity, and healthy diet. Overall, available guidelines lacked specific recommendations for CVR management in older adults. The comparative analysis of the guidelines showed general consistency for lifestyle-related recommendations. Key differences, identified mostly in methods used to assess the overall CVR, did not hamper the intervention design. Minor country-specific adaptations were implemented to maximize the intervention feasibility in each country. CONCLUSION: Despite differences in CVR management within the countries considered, it was possible to design and implement the HATICE multidomain intervention. The study can help define preventative strategies for dementia and CVD that are applicable internationally.
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Barbera et al. (2018) conducted an RCT in Cardiovascular disease and cognitive impairment (n=2,500). Internet-based multidomain intervention (HATICE) was evaluated on Cardiovascular risk profile improvement. An internet-based multidomain intervention was successfully designed for over 2500 community-dwelling older adults aged 65+ to improve cardiovascular risk profiles across three European countries.
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