Key result
Cardiac ultrasonic tissue characterization may enable noninvasive detection of amyloid, myofibrillar disorientation, and vascular pathology.
Why the study?
A technique that defines the physical state of cardiac tissue beyond size and motion visualization was needed for potential clinical applications.
Cardiac ultrasonic tissue characterization is a promising technique for defining the physical state of tissue, with potential applications in detecting amyloidosis and hypertrophic cardiomyopathy.
Should not yet change practice for amyloid or HCM evaluation; leaves open clinical role pending prospective validation.
This new variation on an old technique can actually define the physical state of a tissue--not merely visualize its size and motion. Clinical use awaits technologic refinements, but potential applications include noninvasive detection of amyloid protein, of myofibrillar disorientation characteristic of idiopathic hypertrophic subaortic stenosis, and of various kinds of vascular pathology.
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Miller et al. (1982) studied this question. Cardiac ultrasonic tissue characterization defines the physical state of tissue, potentially allowing noninvasive detection of amyloid protein, myofibrillar disorientation, and vascular pathology.
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