Key result
Cardiac MRI detects left ventricular noncompaction in ~71% of idiopathic DCM cases, often alongside neuromuscular disorders.
Why the study?
The associations of idiopathic dilated cardiomyopathy with left ventricular hypertrabeculation/noncompaction and neuromuscular disorders, and the role of cardiac magnetic resonance imaging in IDC, were not well characterized.
Does cardiac magnetic resonance imaging and neurological evaluation identify left ventricular hypertrabeculation and neuromuscular disorders in patients with idiopathic dilated cardiomyopathy?
Observational (n=7)
Does cardiac magnetic resonance imaging and neurological evaluation identify left ventricular hypertrabeculation and neuromuscular disorders in patients with idiopathic dilated cardiomyopathy?
Patients with idiopathic dilated cardiomyopathy frequently exhibit left ventricular hypertrabeculation and neuromuscular disorders, suggesting a need for neurological evaluation and CMRI when echocardiography is inadequate.
OBJECTIVE: Our aim was to assess 1) the association of idiopathic dilative cardiomyopathy (IDC) and left ventricular hypertrabeculation/noncompaction (LVHT), 2) the use of cardiac magnetic resonance imaging (CMRI) in IDC and 3) the association of IDC and neuromuscular disorders (NMD). METHODS: Patients in whom coronary heart disease had been excluded by coronary angiography and whose left ventricular end diastolic diameter was > 59 mm and fractional shortening < 25% with no other causes of cardiac dysfunction, were invited to participate. RESULTS: Among 25 patients, 18 refused CMRI (claustrophobia n = 13, inability to lie flat n = 5), thus 7 patients (2 female, 47-66 years) were included. LVHT was found in 5/7 cases. In 4/5 patients who were neurologically investigated, a NMD was found. In 2/7 cases echocardiography failed to visualise the ventricular apex. CONCLUSIONS: Patients with IDC should be investigated neurologically. In IDC patients with poor echocardiographic quality CMRI should be applied.
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Stöllberger et al. (2004) conducted an observational in Idiopathic dilated cardiomyopathy (IDC) (n=7). Cardiac magnetic resonance imaging (CMRI) and neurological investigation was evaluated on Presence of left ventricular hypertrabeculation/noncompaction (LVHT) and neuromuscular disorders (NMD). Among 7 patients with idiopathic dilated cardiomyopathy, cardiac magnetic resonance imaging identified left ventricular hypertrabeculation/noncompaction in 5 cases, and 4 had neuromuscular disorders.
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