Key result
LVNC affects ~4% of heart failure patients and is diagnosed primarily via Doppler echocardiogram.
Why the study?
Left ventricular non-compaction is a recently recognized rare cardiomyopathy with variable clinical manifestations and unclear prevalence and management.
Left ventricular non-compaction is a rare, recently recognized cardiomyopathy requiring Doppler echocardiography for diagnosis and symptomatic management for its highly variable clinical manifestations.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to LVNC in HF; review leaves open optimal management and prognosis data.
Left ventricular non-compaction is a recently recognized, rare form of cardiomyopathy. It is based on the arrest of endomyocardial morphogenesis during embryogenesis. It was first described in 1984 by Engberding who described it as isolated 'sinusoids' within the LV. Right now its prevalence is estimated at 0.014 to 1.3 and 3-4% in heart failure patients. Its clinical manifestations are highly variable, ranging from no symptoms to disabling congestive heart failure, arrhythmias, and systemic thromboemboli. Doppler Echocardiogram is considered the diagnostic procedure of choice and treatment is symptomatic management of its symptoms and complications.
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Goud et al. (2016) conducted a review in Left ventricular non-compaction cardiomyopathy. Left ventricular non-compaction is a rare cardiomyopathy with a prevalence of 3-4% in heart failure patients, presenting with variable symptoms and diagnosed primarily via Doppler echocardiogram.
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