Key result
Recent NCCN guidelines direct management and prognostication for adult soft tissue sarcomas.
Why the study?
Adult soft tissue sarcomas are heterogeneous neoplasms with significant incidence and mortality, necessitating updated summaries of diagnosis and management guidelines.
This review provides a summary of current guidelines, staging, and prognostic factors for the management of adult soft tissue sarcomas.
Aids application of recent NCCN guidelines for heterogeneous adult STS; leaves open need for subtype-specific prospective validation.
Adult soft tissue sarcomas (STSs) are heterogeneous neoplasms that account for 11,410 new diagnoses and 4,390 deaths per year. This article summarizes recent NCCN guidelines for diagnosis and management of STSs of the extremities and retroperitoneum, as well as gastrointestinal stromal tumors (GIST). AJCC staging and recently reported NCDB data regarding outcomes are reviewed. Currently accepted STS prognostic variables are presented, as are future directions regarding the utility of molecular prognosticators and nomograms.
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Kneisl et al. (2014) conducted a review in Adult soft tissue sarcomas. Adult soft tissue sarcomas are heterogeneous neoplasms accounting for 11,410 new diagnoses and 4,390 deaths per year, with management and prognostication guided by recent NCCN guidelines.
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