Key result
Toe-tapping heel pin dual-task detects mild cognitive impairment with 0.97 AUC, outperforming standard walking.
Why the study?
Motor and Cognitive Dual-Task approaches represent an innovative chance to assess Mild Cognitive Impairment and may enrich clinical tools for early detection.
Do novel motor and cognitive dual-task approaches (FTAP, TTHP) improve the detection of Mild Cognitive Impairment compared to established methods?
Cross-Sectional (n=44)
Yes
Do novel motor and cognitive dual-task approaches (FTAP, TTHP) improve the detection of Mild Cognitive Impairment compared to established methods?
Effect estimate: AUC 0.97
Absolute Event Rate: 0.97% vs 0.92%
Novel motor and cognitive dual-task approaches like fore-finger and toe-tapping show high diagnostic performance for identifying mild cognitive impairment.
May support MCI screening in practice; leaves open prospective validation before routine use.
Motor and Cognitive Dual-Task (MCDT) represents an innovative chance to assess Mild Cognitive Impairment (MCI). We compare two novel MCDTs, fore-finger tapping (FTAP), toe-tapping (TTHP), to gold standards for cognitive screening (Mini-Mental State Examination-MMSE), and to a well-established MCDT (GAIT). We administered the aforementioned MCDTs to 44 subjects (MCIs and controls). Motor parameters were extracted, and correlations with MMSE investigated. Logistic regression models were built, and AUC areas computed. Spearman's correlation demonstrated that FTAP and TTHP significantly correlate with MMSE, at each cognitive load. AUC areas computed report similar (FTAP, 0.87), and even higher (TTHP, 0.97) capability to identify MCIs, if compared to GAIT (0.92). We investigated the use of novel MCDT approaches to assess MCI, aiming to enrich the clinical repertoire with objective and non-invasive tools. Our protocol shows good correlations with MMSE, and reaches high performances in identifying MCI, adopting simpler exercises.
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Mancioppi et al. (2021) conducted a cross-sectional in Mild Cognitive Impairment (MCI) (n=44). Fore-finger tapping (FTAP) and toe-tapping (TTHP) dual-tasks vs. Walking dual-task (GAIT) was evaluated on Capability to identify Mild Cognitive Impairment (Area Under the Curve) (AUC 0.97). The toe-tapping heel pin dual-task at high cognitive load identified Mild Cognitive Impairment with an AUC of 0.97 (96% specificity, 88% sensitivity), outperforming the standard walking dual-task.
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