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Objectives This research aimed to identify the factors that encourage or discourage participation in health research. Investigators sought to hear directly from community members about their concerns, ideas, and approaches that would increase their willingness to participate, as well as their readiness for medical procedures involved in the research process. Method Data were collected through focus group interviews conducted in four Mississippi counties. Each county was represented by one focus group of 10–12 diverse participants. The interviews were digitally recorded, transcribed, and then analyzed using thematic analysis. Results Two major themes emerged: (1) Encouragement to Participate and (2) Barriers to Participation. Factors that encouraged participation included (1) the involvement of trusted community stakeholders, (2) a desire to contribute to the community, (3) opportunities to improve personal health, and (4) receiving individualized health feedback. Barriers to participation included a (1) lack of trust, (2) time constraints, and (3) challenges related to location and transportation. Conclusions While participants had little prior experience with health research, they expressed a willingness to engage in future studies. Trust was a key factor influencing research participation across all focus groups. This project provides a model for incorporating community feedback, concerns, and recommendations into the design and execution of research in rural areas.
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Ferrell et al. (2025) studied this question.
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