All articles of this category An efficient synthesis of 3,4-dihydropyrimidines using bismuth chloride as a catalyst from an aldehyde, β -keto ester and urea in acetonitrile is described. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of good yields (56-97%). Biginelli reaction - dihydropyrimidinones - bismuth chloride - one-pot condensation - synthesis
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Ramalinga et al. (2001) studied this question.