Key result
Vitamin D supplementation linked to ~97% fewer PVCs in a pediatric deficiency case.
Why the study?
The exact cause of premature ventricular contractions originating from the right ventricular outflow tract in patients without structural heart disease remains unknown, and the role of vitamin D deficiency in this context is unclear.
Does vitamin D supplementation eliminate premature ventricular contractions in a pediatric patient with vitamin D deficiency?
Case Report (n=2)
No
Does vitamin D supplementation eliminate premature ventricular contractions in a pediatric patient with vitamin D deficiency?
Vitamin D deficiency may be associated with frequent RVOT PVCs in children, which can resolve with appropriate vitamin D supplementation.
Answers are grounded in this paper and cite their sources.
May resolve PVCs in vitamin D-deficient children; hypothesis-generating and should not change practice.
Vitamin D receptor is present in almost every cell of the body. Although some studies have suggested that values >30ng/ml would be sufficient, there is no consensus on the optimal values of serum vitamin D. Vitamin D deficiency can lead to “benign” manifestations, such as back pain, joint pain, fatigue, and heavy sweating. Premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT) are considered “benign,” as they occur in patients without structural heart disease and their exact cause remains unknown. We describe the case of a 10-year-old boy with frequent PVCs and vitamin D deficiency that was corrected after vitamin D supplementation. On the contrary, his twin brother had normal serum vitamin D and no PVCs. The disappearance of PVCs occurred after treatment with vitamin D 2000 IU/day.
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Cismaru et al. (2021) conducted a case report in Vitamin D deficiency and Premature Ventricular Contractions (n=2). Vitamin D vs. Baseline was evaluated on Number of PVCs per 24 hours. Vitamin D supplementation of 2000 IU/day for 10 months in a 10-year-old boy with vitamin D deficiency reduced premature ventricular contractions from 47,640 to 1,400 per 24 hours.
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