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Measurable residual disease evaluated by flow cytometry using leukemia associated immune phenotypes following allogeneic stem cell transplantation is associated with high relapse rates in patients with acute myeloid leukemia.Leuk Lymphoma.2020;61(3):745-748.20.US Food and Drug Administration.Hematologic malignancies: regulatory considerations for use of minimal residual disease in development of drug and biological products for treatment.Available at: https://www. fda.gov/regulatory-information/search-fda-guidance-documents/ hematologic-malignancies-regulatory-considerations-use-minimal- residual-disease-development-drug-and.Accessed 23 April 2020.21.US National Library of Medicine.Evaluation of measurable residual disease in patients with acute myeloid leukemia as surrogate endpoint for survival.https://clinicaltrials.gov/show/NCT03549351.
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Chevillon et al. (2020) studied this question.
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