Synthesis, Cell Viability, and Flow Cytometric Fluorescence Pulse Width Analysis of Dendrimers with Indazoles Surface Unit

Dendrimers with indazole surface units were synthesized up to second generation in good yields, and the MTT cell proliferation assay was carried out with A549 lung adenocarcinoma cell lines. The cell viability and the flow cytometry analysis shows that increased mitochondrial activity was concomitant with increased mitochondrial biomass with no loss of mitochondrial membrane potential or cell death.