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Objective: To investigate the clinical characteristics and predictors of postoperative recurrence in sinonasal inverted papilloma (SNIP). Methods: A retrospective cohort study of 53 SNIP patients treated at Zhengzhou University Hospital (2019-2023) was conducted. Patients were stratified into primary (n=34) and recurrent (n=19) cohorts. Clinical variables were analyzed using univariate and multivariate logistic regression. Results: Smoking (OR=10.08, 95% CI=1.32-77.15), prior surgery (OR=17.26, 95% CI=2.69-110.76), and ipsilateral involvement (OR=7.79, 95% CI=1.05-57.99) emerged as independent recurrence predictors (P<0.05). Krouse staging (T3 vs. T1-T2) showed no significant association (P=0.198). Conclusion: Comprehensive evaluation of smoking history, surgical history, and lesion laterality is critical for recurrence risk stratification in SNIP management.
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Li et al. (2025) studied this question.
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