Key result
Medical management of acute type A aortic dissection after prior cardiac surgery carries ~20% mortality.
Why the study?
The optimal initial management strategy for patients with acute type A aortic dissection who had prior cardiac surgery was uncertain.
Does medical treatment prevent mortality in patients with acute type A aortic dissection who had prior cardiac surgery?
Observational (n=10)
Does medical treatment prevent mortality in patients with acute type A aortic dissection who had prior cardiac surgery?
Medical treatment may be a viable initial management strategy for acute type A aortic dissection in patients with prior cardiac surgery, potentially avoiding the need for emergency surgery.
Initial medical management may be considered in post-surgical ATAAD; hypothesis-generating and should not yet change practice.
BACKGROUND: Acute type A aortic dissection (ATAAD) is a life-threatening disease entity. Untreated, it usually results in death due to rupture of the proximal aorta into the pericardial cavity, leading to cardiac tamponade. Should patients who have had prior cardiac surgery presenting with ATAAD be treated emergently with surgery, or should they be managed medically? We herein present preliminary evidence that suggests that medical treatment, at least initially, is the best option for these patients. Surgery is indicated in the follow-up, depending on increased size of the dissection or aorta, or to prevent or treat complications. PATIENTS AND METHODS: From January 2004 to November 2009, ten consecutive male patients with prior cardiac surgery were admitted to hospital with the diagnosis of ATAAD. Mean age was 61.90 +/- 14.68 years (range, 36 to 79 years), with nine (90%) males and one (10%) female. All were treated medically as the definitive form of management. RESULTS: Mean follow-up duration was 14.62 +/- 11.12 months (range, 1 to 31 months). Overall mortality during follow-up was 20% (two patients). Eight patients (80%) are alive and well. CONCLUSIONS: This initial experience with a small, consecutive series of patients, suggests that medical treatment is an option in the initial management of patients with ATAAD who had prior cardiac surgery. It appears that emergency surgery is seldom needed. A larger series of patients and longer follow-up period are needed prior to recommending this treatment approach for such patients.
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Hassan et al. (2010) conducted an observational in Acute type A aortic dissection (ATAAD) with prior cardiac surgery (n=10). Medical treatment was evaluated on Overall mortality. Medical management of acute type A aortic dissection in patients with prior cardiac surgery resulted in an overall mortality of 20% during a mean follow-up of 14.6 months.
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