Key result
PSV detects ~100% of simulated blood vessel changes in a brain phantom model.
Why the study?
The effects of cerebral vasospasm, vasodilation, and haemorrhage under artificial circulation conditions during cardiopulmonary bypass on transcranial duplex ultrasonography measurements were not well understood.
Population
In vitro phantom model simulating artificial circulation during cardiopulmonary bypass
Comparison
Cerebral vasospasm, vasodilation, and haemorrhage conditions
Design
Experimental study using ultrasound system and phantom model
Authors
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PSV may warrant priority in TCD protocols for bypass; leaves open validation in clinical settings.
In a phantom model of cardiopulmonary bypass, Peak Systolic Velocity was the most sensitive transcranial duplex ultrasonography parameter for detecting simulated cerebral vessel pathologies.
Leibuss et al. (2022) studied Cerebral vasospasm, vasodilation, and haemorrhage. Simulated pathological blood vessel conditions (vasospasm, vasodilation, haemorrhage) vs. Conditionally healthy blood vessels was evaluated on Changes in transcranial duplex ultrasonography measurements (PSV, MDV, TAPV). In an artificial circulation brain phantom, Peak Systolic Velocity (PSV) was the most sensitive parameter for detecting blood vessel condition changes, showing alterations in 100% of cases.
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