What question did this study set out to answer?

To review clinical evidence on hypertension as an independent predictor of COVID-19 severity and assess the impacts of blood pressure levels and antihypertensive therapies.

February 17, 2021Frontiers in Cardiovascular MedicineOpen Access

Hypertension and COVID-19: Ongoing Controversies

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Authors

MTMarijana TadićCardiac Imaging SSSahrai SaeedStructural Heart Disease GGGuıdo GrassıGeneral / Preventive / Lipids

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Implication

Review reveals complex interactions between blood pressure and severity in COVID-19 patients, indicating antihypertensive therapies do not worsen clinical outcomes.

Key Points

To review clinical evidence on hypertension as an independent predictor of COVID-19 severity and assess the impacts of blood pressure levels and antihypertensive therapies.
Synthesized observational studies, clinical reports, and meta-analyses examining hypertensive COVID-19 cohorts.
Evaluated the prognostic distinction between chronic and newly diagnosed hypertension alongside blood pressure measurements.
Assessed clinical outcomes associated with the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs).
Initial concerns regarding ACEI and ARB therapy increasing the risk of adverse outcomes were overturned by large-scale studies and meta-analyses showing no increased risk.
Evidence remains inconclusive regarding whether hypertension independently predicts COVID-19 severity apart from related comorbidities like diabetes and obesity.
The specific prognostic roles of blood pressure levels and newly diagnosed versus chronic hypertension remain insufficiently characterized.

Cite This Study

Tadić et al. (2021) studied this question.

synapsesocial.com/papers/6aadeb3a64f913cc7400df82 https://doi.org/10.3389/fcvm.2021.639222

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Implication

Review reveals complex interactions between blood pressure and severity in COVID-19 patients, indicating antihypertensive therapies do not worsen clinical outcomes.

Hypertension and COVID-19: Ongoing Controversies

Discussion

Member takes

Implication

Key Points

Cite This Study

Hypertension and COVID-19: Ongoing Controversies

Discussion

Member takes

Implication

Key Points

Cite This Study

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