Key result
Transient exercise-induced LBBB reveals underlying double-vessel CAD in an asymptomatic woman.
Why the study?
Exercise-induced left bundle branch block (EI-LBBB) is a rare phenomenon during exercise testing that may indicate underlying ischemia and coronary artery disease.
Case Report (n=1)
No
Exercise-induced left bundle branch block during stress testing can be a direct marker of underlying ischemia and coronary artery disease.
Transient exercise-induced LBBB may indicate underlying CAD in asymptomatic patients; this case report leaves open its diagnostic role pending larger studies.
EI-LBBB represents a rare phenomenon observed during electrocardiographic evaluation in response to exercise. We present an asymptomatic patient referred for cardiac fitness before tympanoplasty surgery. During the treadmill exercise test, the patient developed a left bundle branch block, which reverted spontaneously in the recovery phase. A coronary angiogram revealed double vessel disease involving the left anterior descending and left circumflex arteries. The occurrence of EI-LBBB during stress tests like the treadmill test (TMT) can be a direct marker of underlying ischemia and underlying coronary artery disease as seen in our case.
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Samdesi et al. (2025) conducted a case report in Exercise-induced left bundle branch block (EI-LBBB) (n=1). Exercise stress test (Treadmill test) was evaluated on Development of EI-LBBB and diagnosis of underlying coronary artery disease. A 50-year-old asymptomatic woman developed transient exercise-induced left bundle branch block during a treadmill test, revealing underlying double-vessel coronary artery disease that was successfully treated with stenting.