Key result
Italian AF ablation is linked to similar success but ~56% fewer adverse events than other countries.
Why the study?
The Italian data from the ESC-EHRA EORP atrial fibrillation ablation long-term registry were reported to characterize patient demographics, procedural outcomes, and complication rates.
Does atrial fibrillation ablation in Italy yield similar success and complication rates compared to other countries?
Observational (n=318)
Yes
Does atrial fibrillation ablation in Italy yield similar success and complication rates compared to other countries?
Atrial fibrillation ablation in Italy demonstrates comparable 1-year success rates to other European countries but with significantly lower adverse event rates.
AF ablation in Italy may offer improved safety; observational data leaves open generalizability and causal factors.
AIM: To report the Italian data deriving from the European Society of Cardiology-EURObservational Research Program atrial fibrillation ablation long-term registry. METHODS AND RESULTS: Ten Italian centers enrolled up to 50 consecutive patients undergoing atrial fibrillation ablation. Of the 318 patients included, 5 (1.6%) did not undergo catheter ablation, 1 had ablation partially done and 62 were lost at 1-year follow-up. Women were less represented (23.6%) and the median age was 60.0 years. A total of 195 patients (62.3%) suffered paroxysmal atrial fibrillation, whereas only 9 (2.9%) had long-standing persistent atrial fibrillation. Most Italian patients (92.3%) were symptomatic but suffering fewer symptomatic events than patients enrolled in other countries (median of two events in the month preceding the ablation vs. three, respectively; P < 0.0001). The main finding of the study is that the success rate at 1 year, with and without antiarrhythmic drugs, was 76.4%, consistently with other participating countries (73.4%). This result was obtained however, with a significantly lower prevalence of 1-year adverse events (7.3 vs. 16.6%, P < 0.0001). Procedure duration and fluoroscopy total time resulted as being shorter in Italy (145 vs. 160, P = 0.0005 and 16.9 vs. 20.0 min, P = 0.0018, respectively); however, the radiation dose per BSA was greater (37.5 vs. 26.0 mGy/cm, P = 0.0022). CONCLUSION: The demographic characteristics of patients undergoing atrial fibrillation ablation are similar to those reported in other countries. The success rate in Italy is consistent with those in other countries, whereas the complications rate is lower.
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Anselmino et al. (2020) conducted an observational in Atrial fibrillation (n=318). Atrial fibrillation ablation vs. Patients enrolled in other participating countries was evaluated on Success rate at 1 year, with and without antiarrhythmic drugs. Atrial fibrillation ablation in Italy had a 1-year success rate of 76.4%, similar to other countries (73.4%), but with significantly fewer 1-year adverse events (7.3% vs 16.6%, P<0.0001).
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