Key result
Anticoagulant therapy resolves LV apical thrombus and wall motion abnormalities in a Takotsubo cardiomyopathy case.
Why the study?
Takotsubo cardiomyopathy can be complicated by left ventricular apical thrombus, and optimal management with anticoagulation until wall motion abnormalities improve is not well established.
Does anticoagulant therapy resolve apical thrombus and wall motion abnormalities in a patient with Takotsubo cardiomyopathy?
Does anticoagulant therapy resolve apical thrombus and wall motion abnormalities in a patient with Takotsubo cardiomyopathy?
Anticoagulant therapy may be effective in resolving left ventricular apical thrombus associated with Takotsubo cardiomyopathy until wall motion abnormalities improve.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for short-term anticoagulation in Takotsubo with apical thrombus; prospective trials needed before clinical adoption.
We report a case of Takotsubo cardiomyopathy complicated by left ventricular apical thrombus in a young woman; the thrombus and wall motion abnormalities disappeared after 3 weeks of anticoagulant therapy. These findings suggest that appropriate anticoagulation therapy should be performed in patients with Takotsubo cardiomyopathy until wall motion abnormalities improve.
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Tobar et al. (2009) studied this question. Anticoagulant therapy for 3 weeks successfully resolved a left ventricular apical thrombus and wall motion abnormalities in a young woman with Takotsubo cardiomyopathy.
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