Key result
Volumetric central body fat analysis offers no predictive advantage over BMI for hypertension and diabetes.
Why the study?
Central adipose tissue is recognized as a risk factor for cardiometabolic disorders, but the efficacy of volumetric 3D analysis of central adipose tissue in predicting disease needed evaluation.
Does volumetric 3D analysis of central body fat accurately predict the incidence of diabetes and hypertension compared to BMI in adults?
Cross-Sectional (n=1,225)
Does volumetric 3D analysis of central body fat accurately predict the incidence of diabetes and hypertension compared to BMI in adults?
p-value: p=<0.0001
Volumetric 3D analysis of central body fat via CT scan is highly predictive of hypertension and type 2 diabetes, but performs equally to simple BMI measurement.
Volumetric central fat analysis matches BMI for hypertension and diabetes prediction; should not yet change practice and leaves open incremental value of imaging.
BACKGROUND: Central adipose tissue is appreciated as a risk factor for cardiometabolic disorders. The purpose of this study was to determine the efficacy of a volumetric 3D analysis of central adipose tissue in predicting disease. Full body computerized tomography (CT) scans were obtained from 1225 female (518) and male (707) subjects, aged 18-88. Percent central body fat (%cBF) was determined by quantifying the adipose tissue volume from the dome of the liver to the pubic symphysis. Calcium score was determined from the calcium content of coronary arteries. Relationships between %cBF, BMI, and several cardiometabolic disorders were assessed controlling for age, sex, and race. RESULTS: Higher %cBF was significantly greater for those with type 2 diabetes and hypertension, but not stroke or hypercholesterolemia. Simple anthropometric determination of BMI equally correlated with diabetes and hypertension as central body fat. Calcium scoring significantly correlated with all measurements of cardiovascular health, including hypertension, hypercholesterolemia, and heart disease. CONCLUSIONS: Central body fat and BMI equally and highly predict incidence of hypertension and type 2 diabetes.
No takes yet. Share an insight, caveat, or question.
Gibby et al. (2015) conducted a cross-sectional in Cardiometabolic disorders (diabetes and hypertension) (n=1,225). Percent central body fat (%cBF) and BMI vs. Normal weight / lower adiposity was evaluated on Incidence of hypertension and type 2 diabetes (p=<0.0001). Volumetric analysis of percent central body fat and BMI were equally predictive of hypertension and type 2 diabetes, with overweight and obese individuals showing a 2- to 3-fold increased likelihood of hypertension and a 4- to 9-fold increased likelihood of diabetes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: