Key result
New macrovascular complications and neuropathy are linked to moderate reductions in quality of life.
Why the study?
Micro- and macrovascular complications of type 2 diabetes increase morbidity and mortality and may worsen quality of life, but prospective data on their impact are limited.
Does the development of micro- and macrovascular complications reduce quality of life in patients with type 2 diabetes?
Cohort (n=7,830)
Yes
Does the development of micro- and macrovascular complications reduce quality of life in patients with type 2 diabetes?
Effect estimate: reduction in SF-36 PCS (range 0.7 to 1.6 points) and MCS (2.6 points)
The development of macrovascular complications and neuropathy in patients with type 2 diabetes is associated with significant decreases in both physical and mental quality of life.
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QoL monitoring may be warranted after new macrovascular complications or neuropathy in T2D; leaves open causal effects of prevention.
Arnold et al. (2022) conducted a cohort in Type 2 diabetes (n=7,830). Development of micro- and macrovascular complications vs. No new complications was evaluated on Quality of life assessed with the SF-36 Physical (PCS) and Mental Components Summary (MCS) scores (reduction in SF-36 PCS (range 0.7 to 1.6 points) and MCS (2.6 points)). Development of new macrovascular complications and neuropathy was associated with moderate reductions in physical (0.7-1.6 points) and mental (2.6 points) quality of life scores.
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