Mean Platelet Volume in Acute Appendicitis a Case-Control Study

Background: Acute appendicitis is the main causeof surgical acute abdomen in productive ages, with their main incidence between 15 and 35 years.The mean platelet volume is currently considered as an acute phase reactant, it is considered an indicator inversely proportional to the process of systemic inflammatory response, it has been promoted as a biomarker-type study object with good diagnostic and prognostic potential for acute appendicitis processes Material and Methods: The study was developed retrospectively between February 2018 and February 2020, comparing Mean Platelet Volume in male patient in ages between 15-35 years old in two groups.Appendicitis group confirmed by histopathology and their control group, patients admitted for elective inguinal hernia.Values of leukocytes, neutrophils, MPV, were used for their analysis.Statistical analysis was performed with X2 test for age and numbers ofleukocytes, neutrophil count, platelets and MPV.Results: In the appendicitis group Pearson correlation was performed with control group: appendicitis with respect to leukocytes, neutrophils and MPV.Results: Statistically significant differences were found in leukocytes and MPV between the two groups.In the VPM values in the appendicitis group, an average of 8,2 ± 0.93 is observed and in the control group, values of 9.2 ± 1.15 are observed with a statistically significant difference with p <0.05.Conclusion: Although quite practical, there is insufficient evidence to recommend the systematic use od mean platelet volume as diagnostic criteria for acute appendicitis, multiples studies suggest its use with wide range sensibility.