Key result
Multidisciplinary emergency management resolves life-threatening amniotic fluid embolism and DIC after early partial molar pregnancy.
Why the study?
Disseminated intravascular coagulation (DIC) in pregnancy is rare but increases with complications such as amniotic fluid embolism syndrome (AFES).
Case Report (n=1)
Supports multidisciplinary management in rare AFE-DIC with molar pregnancy; leaves open need for systematic data collection.
Disseminated intravascular coagulation (DIC) is a disruption of hemostasis and imbalance between thrombosis and thrombolysis. DIC can result in life-threatening bleeding, clot formation, and multi-system end organ damage. Although the prevalence of DIC in pregnancy is low, ranging from 0.03-0.35%, the prevalence increases in pregnancies complicated by comorbidities such as placental abruption, postpartum hemorrhage, pre-eclampsia, hemolysis elevated liver enzymes and low platelets (HELLP syndrome) and pregnancies complicated by amniotic fluid embolism syndrome (AFES).
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A et al. (2018) conducted a case report in Amniotic fluid embolism and disseminated intravascular coagulation in an early molar pregnancy (n=1). Multidisciplinary emergency management (massive transfusion, IVC filter, uterine artery embolization, hysterectomy) was evaluated on Patient survival and resolution of DIC. A 33-year-old woman with an early partial molar pregnancy survived life-threatening amniotic fluid embolism and disseminated intravascular coagulation following multidisciplinary emergency management.
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