Complete Genome of Acute Rheumatic Fever-Associated Serotype M5 Streptococcus pyogenes Strain Manfredo

Matthew T. G. Holden; Annabel Scott; Inna Cherevach; Tracey Chillingworth; Carol Churcher; Ann Cronin; Linda Dowd; Theresa Feltwell; N. Hamlin; S. Holroyd; Kay Jagels; Sharon Moule; Karen Mungall; Michael A. Quail; Claire Price; Ester Rabbinowitsch; Sarah Sharp; Jason Skelton; Sally Whitehead; Bart Barrell; Michael Kehoe; Julian Parkhill

doi:10.1128/jb.01227-06

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Abstract

Comparisons of the 1.84-Mb genome of serotype M5 Streptococcus pyogenes strain Manfredo with previously sequenced genomes emphasized the role of prophages in diversification of S. pyogenes and the close relationship between strain Manfredo and MGAS8232, another acute rheumatic fever-associated strain.

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Holden et al. (2007) studied this question.

synapsesocial.com/papers/6aae0c6b6eec3421f44f6e3a https://doi.org/10.1128/jb.01227-06

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Complete Genome of Acute Rheumatic Fever-Associated Serotype M5 Streptococcus pyogenes Strain Manfredo

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Complete Genome of Acute Rheumatic Fever-Associated Serotype M5 Streptococcus pyogenes Strain Manfredo

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