Researchers should beware of side-reactions when using iodonium salts dissolved in DMSO due to unexpected arylation.
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Unexpected arylation in DMSO warrants solvent caution for iodonium reagents; leaves open mechanistic confirmation and reaction scope.
Roffi et al. (2015) studied this question. Heating diphenyliodonium triflate in DMSO was evaluated on Formation of 2-thiomethylphenols. Heating diphenyliodonium triflate in DMSO leads to an unexpected arylation reaction and the formation of 2-thiomethylphenols.
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