Key result
Tightening bifurcation asymmetry limits in coronary models increases intravascular volume without altering the pressure profile.
Why the study?
Coronary arterial tree models generated by constrained constructive optimization resemble real trees except for very asymmetric bifurcations, and the impact of limiting bifurcation asymmetry on model structure is unclear.
Population
Computational models of coronary arterial trees generated by constrained constructive optimization
Comparison
Model trees grown with different limits on bifurcation asymmetry imposed
Design
Computational modeling study using constrained constructive optimization algorithm
Authors
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Bifurcation asymmetry limits alter coronary model morphometrics without affecting pressure; leaves open optimal thresholds for physiological simulations.
Local bifurcation asymmetry limits in computational models of coronary arterial trees determine global structure without altering functional pressure profiles.
Schreiner et al. (1997) studied Coronary arterial tree models. Imposing a limit on the asymmetry of bifurcations vs. Models grown with different limits imposed was evaluated on Effects on structure and pressure profile. Tightening the limit to bifurcation asymmetry in coronary arterial tree models increased total intravascular volume, surface, and segment lengths, while the pressure profile remained unaffected.
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