Key result
Higher Life's Simple 7 adherence linked to ~9% lower prevalence of chronic constipation and diarrhea.
Why the study?
Chronic gastrointestinal disorders like constipation and diarrhea significantly impact public health, and the influence of Life’s Simple 7 health behaviors on bowel health is unclear.
Does adherence to Life's Simple 7 health behaviors reduce the prevalence of chronic constipation and diarrhea in U.S. adults?
Cross-Sectional (n=12,912)
Does adherence to Life's Simple 7 health behaviors reduce the prevalence of chronic constipation and diarrhea in U.S. adults?
Odds Ratio: 0.914 (95% CI 0.864–0.966)
p-value: p=0.003
Adherence to cardiovascular health metrics (Life's Simple 7) is associated with a lower prevalence of chronic constipation and diarrhea in U.S. adults.
Supports CV health promotion for bowel symptoms; leaves open causality and needs prospective confirmation.
Background Chronic gastrointestinal disorders, such as chronic constipation and diarrhea, pose significant public health challenges, affecting quality of life and healthcare costs. Life’s Simple 7 (LS7), established by the American Heart Association, encompasses essential health behaviors that may influence bowel health. Methods We utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2010, focusing on adults aged 20 years and older. A total of 12,912 participants were included in the analysis. Bowel health was assessed through self-reported questionnaires, while LS7 was evaluated based on seven components: smoking status, physical activity, dietary quality, BMI, blood pressure, blood glucose, and blood cholesterol. Survey-weighted logistic regression models were employed to assess the associations between LS7 and chronic constipation and diarrhea, adjusting for various demographic and health-related covariates. Results Our findings revealed a significant inverse association between LS7 adherence and the prevalence of chronic constipation (OR: 0.914, 95% CI: 0.864–0.966, p = 0.003) and chronic diarrhea (OR: 0.883, 95% CI: 0.856–0.912, p < 0.0001). The protective effect of LS7 was more pronounced among males and individuals with a BMI under 30 kg/m2 for chronic constipation, and among younger adults and those without hypertension for chronic diarrhea. Restricted cubic spline analyses indicated a dose–response relationship, particularly for chronic diarrhea. Conclusion This study highlights the protective role of LS7 in promoting bowel health and preventing chronic constipation and diarrhea. Tailoring public health interventions based on demographic and health characteristics may enhance the effectiveness of strategies aimed at improving gastrointestinal health outcomes.
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Sun et al. (2025) conducted a cross-sectional in Chronic bowel disorders (chronic constipation and chronic diarrhea) (n=12,912). Life's Simple 7 (LS7) adherence vs. Lower adherence to LS7 was evaluated on Prevalence of chronic constipation (OR 0.914, 95% CI 0.864-0.966, p=0.003). Higher adherence to Life's Simple 7 was significantly associated with a lower prevalence of chronic constipation (OR 0.914) and chronic diarrhea (OR 0.883) among US adults.
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