Case report demonstrates concurrent intestinal tuberculosis and colonic adenocarcinoma in a young adult, highlighting the necessity of multiple biopsies in endemic settings.
Concurrent intestinal tuberculosis and colonic adenocarcinoma are rare and pose significant diagnostic challenges due to overlapping clinical and endoscopic features. We report a 25-year-old woman presenting with right iliac fossa pain, anorexia, and 10-kg weight loss. Colonoscopy showed a proliferative ascending colon growth with adjacent cecal ulcers. Histopathology confirmed adenocarcinoma from the growth, while catridge-based nucleic acid amplification test from the ulcers detected Mycobacterium tuberculosis . The patient received antitubercular therapy, followed by right hemicolectomy and adjuvant folinic acid, 5-fluorouracil, and oxaliplatin chemotherapy. This case emphasizes the importance of obtaining separate biopsies from multiple lesions to identify dual pathology and ensure appropriate sequential management in tuberculosis-endemic regions.
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