The Clinic Pathologic Characteristics and Survival of Patients with Lung Cancer in the West of Iran; A Cross-Sectional Study

Background: Lung cancer (LC) is the most commonly occurring cancer worldwide. Objectives: We aimed to evaluate the clinicopathological characteristics of LC and the survival rates for each type. Methods: In a retrospective study, medical records from 313 LC patients referred to a clinical center in Kermanshah, Iran (2010 - 2019) were extracted and reviewed. Statistical analysis was conducted using SPSS 22 and Stata 15 software. Results: Of the 313 patients, 91 (29.1%) were female and 222 (70.9%) were male, with a mean age of 61.17 ± 14.37 years. Non-small cell carcinoma (NSCLC) was the most common morphology (76.6%), which was associated with smoke exposure. The five-year survival rate, according to the Kaplan-Meier method, was 12%. There were statistically significant differences between gender, age groups, and smoke exposure with tumor classification (P < 0.05). The age group > 50 years was associated with a higher mortality rate in univariate analysis (HR: 2.034; 95% CI: 1.046 - 3.955, P = 0.036). Conclusions: The five-year survival rate of LC was consistent with previous reports worldwide (less than 15%). The age group > 50 years was identified as a risk factor for LC and higher mortality rates.