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The present study has focused on the development of new composite scaffolds based on the combination of zein with bioactive glass for the application in bone tissue engineering. Porous polymeric matrices were produced by the salt leaching technique. By incorporating 45S5 bioactive glass particles the lack of bioactivity can be remedied. However, the addition of bioactive glass is influencing the plasticization behavior of the zein matrix during the salt leaching which negatively affects the compression strength as well as the degradation behavior. This paper describes the process during leaching and explains the different behavior of zein with and without the presence of bioactive glass
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Hum et al. (2018) studied this question.
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