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March 17, 2011Colorectal DiseaseOpen Access

Colorectal cancer in nonagenarians

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Key result

Colorectal surgery is linked to ~44% five-year survival in low-risk nonagenarians compared to no surgery.

  • n=74

Why the study?

The short-term and long-term outcomes of nonagenarians treated for colorectal cancer were not well characterized.

Does colorectal surgery improve survival in nonagenarians with colorectal cancer compared to no surgery?

Population

74 patients aged ≥ 90 years diagnosed with colorectal cancer from 1986 to 2009

Comparison

Surgery (elective or emergency) vs no surgery

Design

Retrospective cohort analysis

Follow-up

Up to 5 years

Authors

JAJuan J. ArenalHospital Universitario Río HortegaCTC. TinocoFLFernando LabargaHospital Universitario Río Hortega

Discussion

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Implication

Supports selective surgery in fit nonagenarians with colorectal cancer; leaves open need for prospective validation before broader adoption.

Study Design

Type

Cohort (n=74)

Structured PICO

Does colorectal surgery improve survival in nonagenarians with colorectal cancer compared to no surgery?

P
Population
74 patients aged ≥ 90 years diagnosed with colorectal cancer between 1986 and 2009, evaluated for surgical outcomes and survival.
E
Exposure
Colorectal surgery (elective or emergency)
C
Comparator
No surgery
O
Outcome
Short-term and long-term outcomes including mortality, morbidity, and survivalhard clinical

Colorectal surgery can be performed with acceptable mortality in nonagenarians with low perioperative risk, offering improved survival compared to non-surgical management.

Cite This Study

Arenal et al. (2011) conducted a cohort in colorectal cancer (n=74). Colorectal surgery vs. No surgery was evaluated on Mortality, morbidity and survival. Colorectal surgery in nonagenarians with low perioperative risk yielded 5% surgical mortality and 44% 5-year survival, whereas no non-surgical patients survived beyond 36 months.

synapsesocial.com/papers/6aae2dac518932a41343bbaahttps://doi.org/10.1111/j.1463-1318.2011.02596.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Colorectal Resection and Primary Anastomosis in Patients Aged 70 and Older: Prospective Study1999 · 51 citations
  2. 2Surgery in the Nineties2000 · 45 citations
  3. 3Outcomes of Surgery in Patients 90 Years of Age and Older1989 · 264 citations
  4. 4Emergent and Elective Colon Surgery in the Extreme Elderly: Do the Results Warrant the Operation?2008 · 22 citations
  5. 5Outcomes of Anesthesia and Surgery in People 100 Years of Age and Older1998 · 62 citations