Key result
High SUVmax on initial FDG PET/CT is linked to poorer prognosis in cutaneous angiosarcoma.
Why the study?
Cutaneous angiosarcoma is a rare soft tissue sarcoma with rapid growth and poor prognosis, and the prognostic value of FDG PET/CT in these patients is unclear.
Does high SUVmax on 18F-FDG PET/CT predict poorer survival in patients with cutaneous angiosarcoma?
Observational (n=18)
No
Does high SUVmax on 18F-FDG PET/CT predict poorer survival in patients with cutaneous angiosarcoma?
High SUVmax on initial 18F-FDG PET/CT is associated with poorer prognosis in patients with cutaneous angiosarcoma, suggesting its utility in selecting therapeutic strategies.
May support FDG PET/CT for risk stratification in cutaneous angiosarcoma; hypothesis-generating and requires prospective validation.
Cutaneous angiosarcoma (CAS) is a rare soft tissue sarcoma with rapid growth and poor prognosis. We retrospectively analyzed the data of 18 patients with CAS who underwent 18F‐Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) at the initial visit to the Department of Dermatology, Okayama University Hospital from September 2006 to March 2016. In the univariate survival analysis, patients with high standardized uptake values (SUVmax) of the primary tumor showed significantly poorer prognosis than those with low SUVmax. Early assessment of prognosis using PET/CT may predict patient survival and is useful in the selection of therapeutic strategies.
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Umemura et al. (2017) conducted an observational in Cutaneous angiosarcoma (n=18). High SUVmax on FDG PET/CT vs. Low SUVmax was evaluated on Survival. High standardized uptake values (SUVmax) on initial FDG PET/CT were associated with significantly poorer prognosis in patients with cutaneous angiosarcoma compared to low SUVmax.
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