Key result
Calcium channel blockers treat diverse conditions beyond angina including hypertension, HCM, arrhythmias, and asthma.
Why the study?
Calcium channel blockers were initially approved for angina pectoris, but recent studies indicate their usefulness in diverse cardiovascular and non-cardiovascular conditions.
Calcium channel blockers have diverse clinical applications beyond angina, including hypertension, arrhythmias, and hypertrophic cardiomyopathy.
May support broader calcium channel blocker use in hypertension and arrhythmias; leaves open need for randomized trials to refine indications.
The calcium channel blockers initially were approved for the treatment of classical and variant angina pectoris. Recent studies indicate that these agents also are useful in such diverse conditions as pulmonary and systemic hypertension, hypertrophic cardiomyopathy, arrhythmias, asthma, Raynaud's syndrome, esophageal spasm, myometrial hyperactivity, cerebral arterial spasm, and migraine.
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Donald A. Weiner (1988) studied this question. Calcium channel blockers are useful for treating diverse conditions including hypertension, hypertrophic cardiomyopathy, arrhythmias, asthma, and Raynaud's syndrome, in addition to angina.
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