Key result
Supine hypotension symptoms in pregnancy are associated with reduced azygos venous flow versus asymptomatic women.
Why the study?
Women with supine hypotensive syndrome may have reduced ability to compensate for hemodynamic changes caused by supine positioning during late pregnancy.
Does supine positioning cause different hemodynamic changes in pregnant women with symptoms of supine hypotensive syndrome compared to asymptomatic women?
Comparison
Supine positioning vs left lateral positioning; symptomatic vs asymptomatic women
Design
Observational study using magnetic resonance imaging
Authors
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Reduced azygos flow may underlie symptoms; hypothesis-generating and should not yet change supine positioning practice in pregnancy.
Observational (n=22)
Does supine positioning cause different hemodynamic changes in pregnant women with symptoms of supine hypotensive syndrome compared to asymptomatic women?
Mean Difference: -0.15 (95% CI -0.3–-0.01)
Pregnant women with symptoms of supine hypotensive syndrome have reduced compensatory azygos venous flow compared to asymptomatic women when in the supine position.
Humphries et al. (2019) conducted an observational in Supine hypotensive syndrome (n=22). Symptoms of supine hypotension vs. No symptoms of supine hypotension was evaluated on Azygos venous flow rate (MD -0.15 L/min, 95% CI -0.30 to -0.01). Pregnant women with symptoms of supine hypotension had a significant reduction in azygos venous flow rate compared to asymptomatic women (mean difference -0.15 L/min; 95% CI -0.30 to -0.01).
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