Key result
Admission stress hyperglycemia in AMI linked to ~5-fold higher in-hospital mortality.
Why the study?
Admission hyperglycemia is associated with adverse cardiovascular events in patients with acute coronary syndrome, but its prognostic value for in-hospital outcomes needs assessment.
Does the presence of stress hyperglycemia on admission predict worse in-hospital outcomes in patients with acute myocardial infarction?
Observational (n=100)
No
Does the presence of stress hyperglycemia on admission predict worse in-hospital outcomes in patients with acute myocardial infarction?
Absolute Event Rate: 9.5% vs 1.75%
p-value: p=0.002
Stress hyperglycemia on admission is a strong independent predictor of in-hospital mortality and complications in patients with acute myocardial infarction.
Stress hyperglycemia may flag higher in-hospital risk in AMI; hypothesis-generating and should not yet change practice.
Background: In acute coronary syndrome (ACS), admission hyperglycemia is associated with adverse cardiovascular events in patients. Objective: To assess the prognostic value of stress hyperglycemia for the in-hospital outcome of patients admitted due to ACS. Methods: This study was conducted on 100 patients admitted with Acute Myocardial Infarction in a tertiary care hospital. Patients were categorized according to their blood sugar level stress hyperglycemia present and absent. Results: 64% of the patients were diagnosed with non-ST-elevation myocardial infarction NSTEMI and 36% were diagnosed with STEMI. Lesions most frequently (84.9%) in the left anterior descending artery (LAD) followed by right coronary artery 65% followed by Circumflex artery (54%) followed by Left Main Coronary Artery (3%). Death in stress hyperglycemia group was four times that of those who were not having hyperglycemia. Conclusion: Stress hyperglycemia is an independent predictive factor for in-hospital complications after ACS. The results highlight the need to assess admission blood glucose concentration in all patients admitted due to ACS, including nondiabetic ones, aiming at identifying those at higher risk for complications.
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Chowda et al. (2023) conducted an observational in Acute Myocardial Infarction (n=100). Stress hyperglycemia vs. Absence of stress hyperglycemia was evaluated on In-hospital death (p=0.002). Stress hyperglycemia on admission in patients with acute myocardial infarction was associated with a significantly higher in-hospital mortality rate (9.5% vs 1.75%, p=0.002) compared to those without stress hyperglycemia.
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