Key result
Preoperative ECG abnormalities show no association with MINS or 1-year MACE.
Why the study?
The evidence regarding preoperative ECG as a predictor of perioperative cardiac complications in high-risk vascular surgery patients is weak.
Do preoperative ECG abnormalities predict myocardial injury or 1-year MACE in patients undergoing high-risk vascular surgery?
Cohort (n=348)
ECG evaluators blinded to outcomes
No
Do preoperative ECG abnormalities predict myocardial injury or 1-year MACE in patients undergoing high-risk vascular surgery?
Preoperative ECG abnormalities do not predict myocardial injury or 1-year MACE in patients undergoing high-risk vascular surgery, challenging the utility of routine preoperative ECG in this setting.
Should not yet change preoperative ECG use in high-risk vascular surgery; hypothesis-generating and requires prospective validation.
BACKGROUND: The current European guidelines recommend that a preoperative electrocardiogram (ECG) should be performed routinely in patients scheduled for high-risk surgery. However, the evidence regarding ECG as a predictor of perioperative cardiac complications is weak. AIM: To evaluate the association of preoperative ECG with short- and long-term outcomes in patients undergoing high-risk vascular procedures. METHODS: This was a substudy of the international Vascular events In noncardiac Surgery patIents cohort evaluatioN (VISION) Study and included consecutive patients undergoing vascular procedures in a single tertiary center. In each patient, a preoperative 12-lead ECG was evaluated by two experienced clinicians following the Polish Cardiac Society recommendations. We performed routine perioperative troponin monitoring at five time points (one preoperative and four postoperative measurements) to evaluate whether preoperative ECG abnormalities are associated with myocardial injury after noncardiac surgery (MINS) and 1-year major adverse cardiovascular events (MACE) including cardiac death, myocardial infarction, and stroke. RESULTS: The study group comprised 348 patients, 80.5% of whom were male and the median age (interquartile range [IQR]) was 65 (59-72) years. The incidence of MINS and 1-year MACE was 18.7% and 14.4%, respectively. Multivariable analysis showed that none of the predefined ECG abnormalities (ST depression, left axis deviation, atrial fibrillation, and bundle branch block) was associated with the incidence of MINS or 1-year MACE. CONCLUSION: This study confirmed that preoperative ECG abnormalities are frequent in patients undergoing high-risk vascular surgery. However, we did not find evidence supporting the relation between preoperative ECG abnormalities and postoperative adverse cardiac outcomes in high-risk patients.
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A 2022 study conducted a cohort in High-risk vascular surgery (n=348). Preoperative electrocardiographic abnormalities vs. Normal preoperative electrocardiogram was evaluated on Myocardial injury after noncardiac surgery (MINS) and 1-year major adverse cardiovascular events (MACE). Preoperative electrocardiographic abnormalities were not significantly associated with the incidence of myocardial injury after noncardiac surgery or 1-year major adverse cardiovascular events.
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