Key result
Bicuspid aortic valve repair yields ~92% freedom from reoperation at seven years.
Why the study?
This study aimed to present long-term outcomes of bicuspid aortic valve repair and analyze factors associated with repair failure and early echocardiographic results.
What are the long-term outcomes and risk factors for failure after bicuspid aortic valve repair in patients with BAV insufficiency?
Cohort (n=206)
No
What are the long-term outcomes and risk factors for failure after bicuspid aortic valve repair in patients with BAV insufficiency?
Bicuspid aortic valve repair provides excellent mid-term durability (91.8% freedom from reoperation at 7 years), with better outcomes associated with Type 0 configuration, circumferential annuloplasty, and sinotubular junction remodeling.
Supports BAV repair in experienced centers for selected anatomy; leaves open need for randomized trials versus replacement.
OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 males (74%)] with BAV insufficiency with or without aortic dilatation underwent elective aortic valve repair performed by a single surgeon with a mean follow-up of 5 ± 3.5 years. The transthoracic echocardiography examinations were reported. RESULTS: There were no deaths during the hospital stay, and all but 1 patient survived the follow-up period (99.5%). Overall, 10 patients (5%) developed severe insufficiency and 2 (1%) developed aortic dilatation requiring reoperation. Freedom from reoperation at 7 years reached 91.8%. Type 2 BAV configuration [hazard ratio (HR) 3.9; 95% confidence interval (CI): 1.01-60; P = 0.049], no sinotubular junction remodelling (HR 7; 95% CI: 1.7-23; P = 0.005), no circumferential annuloplasty (HR 3.9; 95% CI: 1.01-64; P = 0.047) and leaflet resection (HR 5.7; 95% CI 1.2-13. P = 0.017) have been identified as a risk factor of redo operation. Parameters of the postoperative left ventricle reverse remodelling improved significantly early after the operation and later at 2 years evaluation. CONCLUSIONS: The repair of BAV offers good short- and mid-term results providing a significant reverse left ventricular remodelling. Type 0 BAV preoperative configuration, circumferential annuloplasty and sinotubular junction remodelling are associated with better repair durability.
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Jasiński et al. (2021) conducted a cohort in Bicuspid aortic valve insufficiency (n=206). Bicuspid aortic valve repair was evaluated on Freedom from reoperation at 7 years. Bicuspid aortic valve repair achieved 91.8% freedom from reoperation at 7 years, while lack of sinotubular junction remodeling (HR 7) and Type 2 BAV (HR 3.9) increased the risk of redo surgery.