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Nations around the world are working to find the best ways to manage the ongoing coronavirus disease 2019 (COVID-19) pandemic. They are pairing efforts to detect viral infection, prevent transmission, and manage patients who are infected, with knowledge of previous seasonal coronavirus outbreaks and growing experience with COVID-19 to craft best-evidence guidance. Recent data show that as many as 25% of patients who are infected remain asymptomatic, and viral shedding may begin up to 48 hours before symptoms appear.
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Kliger et al. (2020) studied this question.
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