Acute Disseminated Encephalomyelitis Following Zika Virus Infection

A 19-year-old woman presented with a gradual onset of tetraplegia, urinary retention, and reduced level of consciousness. She had a history of Zika virus infection 3 weeks previously, and this was confirmed by polymerase chain reaction assay [1,2]. Neurological examination revealed the presence of bilateral Babinski signs and a Glasgow Coma Scale score of 9. HIV, HTLV-1 antibody, and VDRL test results were negative. Brain and spinal MRI showed multiple hyperintense FLAIR foci in the brain and longitudinally extensive myelitis (fig. 1). We started the patient on methylprednisolone, and her neurological condition improved progressively in a month, with significant improvement in MRI findings (fig. 2).The authors report no disclosure.