Key result
Rheumatoid lung disease is linked to cholesterol pleural effusion in two reported cases.
Why the study?
Cholesterol pleural effusion is a rare condition with limited case reports, and its association with rheumatoid lung disease is not well documented.
Case Report (n=2)
Provides early case evidence linking cholesterol pleural effusion to rheumatoid lung disease, including detailed histological findings.
May support including rheumatoid lung disease in the cholesterol effusion differential; leaves open confirmation in larger cohorts.
AndrewsCholesterol pleural effusion is a rare condition.According to Moll and Fowweather (1940), Malaguti collected 44 cases from the literature up to 1929.However, I have been able to read only 39 case reports since the original by Churton in 1882, the majority being in the non-English literature.This paper describes a further two patients, who are of particular interest in that for the first time there is in one case a full post- mortem report with histological appearances and, in both, evidence that rheumatoid lung disease was an aetiological factor.CASE I P. D., a 39-year-old man employed as a semi-skilled loom mechanic, or tenter, developed rheumatoid arthritis in 1938.Two months before the onset of his arthritis he was said to have had a right-sided pneumonia.In 1951 he was admitted to Bridge of Earn Hospital for further treatment of the arthritis and was found to have a right-sided pleural effusion.Aspiration of this revealed numerous cholesterol crystals, the cell count being 65% lymphocytes and 35% polymorphs, while the fluid was sterile on
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Gayle C. Ferguson (1966) conducted a case report in Cholesterol pleural effusion in rheumatoid lung disease (n=2). Rheumatoid lung disease was evaluated. Two cases of cholesterol pleural effusion were described, providing evidence that rheumatoid lung disease was an aetiological factor.
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